Hiroshi Takayanagi Selected Research

Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)

3/2009	[Molecular mechanism of bone destruction].
4/2007	[Osteoclast differentiation and activation].
2/2005	Stat1-mediated cytoplasmic attenuation in osteoimmunology.
1/2005	Osteoimmunological insight into bone damage in rheumatoid arthritis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hiroshi Takayanagi Research Topics

Disease

16	Bone Resorption 01/2019 - 05/2002
12	Arthritis (Polyarthritis) 08/2020 - 06/2003
11	Inflammation (Inflammations) 01/2021 - 12/2005
8	Osteoporosis 03/2015 - 08/2005
6	Rheumatoid Arthritis 01/2020 - 01/2007
6	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 02/2008
4	Neoplasms (Cancer) 01/2020 - 02/2010
3	Experimental Arthritis 08/2020 - 02/2008
3	Osteopetrosis 03/2008 - 04/2004
2	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2019
2	Bone Diseases (Bone Disease) 03/2014 - 12/2005
2	Rheumatic Diseases (Rheumatism) 12/2009 - 05/2009
1	Hip Dislocation 01/2022
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021
1	Osteomyelitis 01/2021
1	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2021
1	Hypertrophy 08/2020
1	Necrosis 06/2020
1	Carcinogenesis 01/2019
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Immune System Diseases (Immune Disorders) 01/2019
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2019
1	Osteolysis 01/2019
1	Communicable Diseases (Infectious Diseases) 01/2018
1	Lung Neoplasms (Lung Cancer) 10/2017
1	Osteosarcoma (Osteogenic Sarcoma) 01/2017
1	Bone Fractures (Bone Fracture) 03/2016
1	Hypergammaglobulinemia (Hyperimmunoglobulinemia) 03/2015
1	Infertility (Sterility) 05/2014
1	Cleidocranial Dysplasia (Cleidocranial Dysostosis) 01/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2012
1	Joint Diseases (Joint Disease) 05/2012
1	Metabolic Bone Diseases (Osteopenia) 03/2012
1	Vitamin E Deficiency 03/2012
1	Squamous Cell Carcinoma of Head and Neck 02/2010
1	Mouth Neoplasms (Oral Cancer) 02/2010
1	Chagas Disease (American Trypanosomiasis) 07/2009

Drug/Important Bio-Agent (IBA)

11	CytokinesIBA 01/2021 - 12/2005
11	LigandsIBA 01/2020 - 01/2005
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2004
4	Interleukin-17 (Interleukin 17)IBA 01/2021 - 01/2012
4	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 03/2009 - 01/2005
3	Phosphotransferases (Kinase)IBA 01/2020 - 03/2008
3	Semaphorin-3AIBA 01/2019 - 05/2012
3	Antirheumatic Agents (DMARD)IBA 12/2009 - 01/2007
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 02/2010
2	AutoantibodiesIBA 08/2020 - 03/2015
2	Immunoglobulin G (IgG)IBA 01/2019 - 03/2015
2	Denosumab FDA Link 01/2019 - 10/2017
2	CollagenIBA 01/2016 - 01/2014
2	AntigensIBA 01/2015 - 01/2014
2	PlasticsIBA 01/2015 - 01/2014
2	InterleukinsIBA 04/2010 - 11/2006
2	RANK LigandIBA 09/2009 - 12/2005
2	Fc Receptors (Fc Receptor)IBA 07/2007 - 04/2004
1	PeriostinIBA 01/2022
1	Interleukin-4 (Interleukin 4)IBA 01/2021
1	Interleukin-18 (Interleukin 18)IBA 01/2021
1	Butyrates (Butyrate)IBA 08/2020
1	Collagen Type II (Type II Collagen)IBA 08/2020
1	chlorine dioxide (Alcide)IBA 06/2020
1	tyrosine receptor (receptor, tyrosine)IBA 01/2020
1	Proto-Oncogene Proteins c-hckIBA 01/2020
1	Stromal Interaction MoleculesIBA 01/2019
1	Chemotactic FactorsIBA 01/2019
1	Immunoglobulin E (IgE)IBA 01/2019
1	Pharmaceutical PreparationsIBA 10/2017
1	Gonadal Steroid Hormones (Sex Hormones)IBA 10/2017
1	RNA (Ribonucleic Acid)IBA 01/2017
1	FollistatinIBA 01/2017
1	Carrier Proteins (Binding Protein)IBA 01/2017
1	Immunologic Factors (Immunomodulators)IBA 12/2015
1	AntibodiesIBA 12/2015
1	Hormones (Hormone)IBA 09/2015
1	ChemokinesIBA 09/2015
1	Antigen-Antibody Complex (Immune Complex)IBA 03/2015
1	theaflavin-3,3'-digallateIBA 03/2015
1	EndotoxinsIBA 05/2014
1	ibrutinibIBA 03/2014
1	Transcription Factors (Transcription Factor)IBA 01/2014
1	Class Ia Phosphatidylinositol 3-KinaseIBA 12/2012
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 12/2012
1	Adenosine Triphosphate (ATP)IBA 11/2012
1	bone resorption factorIBA 11/2012
1	Mitochondrial DNA (mtDNA)IBA 11/2012
1	MineralsIBA 11/2012
1	CD100 antigenIBA 11/2012
1	OsteoprotegerinIBA 05/2012
1	CateninsIBA 03/2012
1	Tissue Plasminogen Activator (Alteplase)FDA Link 03/2012
1	Tocopherols (Tocopherol)IBA 03/2012
1	ThiazolidinedionesIBA 10/2010
1	Hypoglycemic Agents (Hypoglycemics)IBA 10/2010
1	Conditioned Culture MediaIBA 02/2010
1	Parathyroid Hormone-Related ProteinIBA 02/2010
1	LipopolysaccharidesIBA 09/2009

Therapy/Procedure

2	Therapeutics 07/2007 - 06/2003
1	Disarticulation 01/2022
1	Drug Therapy (Chemotherapy) 11/2019
1	Oral Administration 01/2019